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Jakavi 5 mg Tablets contains the active ingredient Ruxolitinib and belongs to the class of kinase inhibitors. It is an advanced anticancer medication used to treat myelofibrosis, a rare bone marrow cancer that disrupts normal blood cell production. It is also prescribed for polycythemia vera, a condition where the body produces too many red blood cells, particularly in patients who do not respond well to hydroxyurea. Additionally, Jakavi 5mg tablet for GVHD (Graft versus Host Disease) is approved for adults and children aged 12 and above who have not responded adequately to steroid or systemic therapies.

The Jakavi 5mg for myelofibrosis dosage is determined by the physician based on body weight, blood counts, and treatment response. It works by blocking abnormal signalling pathways that drive excessive cell growth, helping to reduce symptoms like spleen enlargement and fatigue.

Patients should avoid this medication if allergic to Ruxolitinib or any of its components. Inform your doctor beforehand if you have a history of tuberculosis, hepatitis B or C, liver or kidney disease, or low blood cell counts. Common side effects include dizziness, headache, swelling, bruising, and reduced platelet levels. Notify your doctor immediately if you experience persistent bleeding or infection.

For affordability, the Jakavi 5mg Tablet price and Ruxolitinib 5mg tablet price in India may vary by pharmacy or region. Patients can buy Jakavi 5mg Tablet online from trusted sources to ensure authenticity. The Novartis Jakavi 5mg price reflects its high-quality manufacturing standards. If unavailable, your doctor may suggest a Jakavi 5mg substitute such as Ruxolix, though Jakavi 5mg vs Ruxolix 5mg comparisons show both have similar efficacy and composition.

Eligible patients can also explore the Jakavi 5mg Patient Assistance Program, which provides financial support to make treatment more accessible. Overall, Jakavi remains a trusted option in modern haematology for managing complex blood and bone marrow disorders.

Uses of Jakavi Tablets

Myelofibrosis
Polycythemia vera
Acute-graft-versus-host disease
Chronic-graft-versus-host disease

How Jakavi Tablet works – Buy Jakavi 5 mg Tablets Online UK

Ruxolitinib, a kinase inhibitor, inhibits dysregulated Janus Associated Kinase (JAK) 1 and JAK2 signaling associated with myelofibrosis and polycythemia vera. By blocking certain enzymes, this medicine can reduce the serious risk of blood or vascular complications in myelofibrosis and polycythemia vera. In GvHD, it reduces the signs and symptoms, improving the disease and survival of transplanted cells.

Interaction of Jakavi 5mg Tablet with other drugs

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional, and supplements and herbal products. Certain medications like fluconazole and other CYP3A4 inhibitors may interact with Jakavi 5mg tablet and reduce its effectiveness by causing undesirable side effects.

Storage conditions

Do not store this medicine above 30°C

Keep the medicine out of reach from children and pets

If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

How to take Jakavi 5mg Tablet

Your doctor will decide the dose and duration of Jakavi 5mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Jakavi 5mg side effects are

Common

Low red and white blood cell counts
Low platelet counts
Dizziness, headache
Bruising
Diarrhea
Infections, including viral infections
Swelling in the face and body
Fatigue or tiredness

Serious 

Severe infections like hepatitis B
Anemia

Bleeding

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