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Mektovi 15 mg Tablets (binimetinib) is a prescription treatment for certain types of cancer. It is used with another medication called encorafenib to treat melanoma, a type of skin cancer, and non-small cell lung cancer (NSCLC).

For Mektovi to work, these cancers must have a specific change in a gene called BRAF. Doctors will test for this gene change before prescribing Mektovi.

For melanoma, Mektovi is administered to patients whose cancer has spread to other parts of the body or cannot be removed with surgery.

For NSCLC, it is used when the cancer has already spread. This medication does not work for all cases of melanoma or lung cancer, only those with the specific BRAF gene change.

People with heart problems, blood clots, eye issues, lung conditions, liver or kidney disease, muscle problems, or high blood pressure should tell their doctor before using this medication.

Pregnant women should avoid Mektovi because it may harm an unborn baby, and women who can become pregnant should use birth control while taking it. Breastfeeding is also not recommended while on this medication.

Before starting Mektovi medication, patients should tell their doctor about all other medications they are taking, including vitamins and herbal supplements.

How Does Mektovi Work? – Buy Mektovi 15 mg tablets in the UK

Mektovi works by blocking specific proteins that help cancer cells grow. It targets two proteins called MEK1 and MEK2, which are part of a larger pathway that sends signals inside cells.

This pathway is always active in some cancers, like melanoma and non-small cell lung cancer, because of a gene change in BRAF.

Mektovi stops these signals, which slows down or even stops cancer cells from growing.

Mektovi is always used with another medication called encorafenib. Together, these two medications work better than either one alone.

They attack cancer cells from different angles, making it harder for the cancer to keep growing.

This combination also helps slow the cancer’s ability to resist treatment, which means the medication can keep working longer.

Dosage Information and Usage – Buy Mektovi 15 mg Tablets online

If you are taking Mektovi, following the correct dose and schedule is important for the best results. Mektovi is used with another medication called encorafenib to treat certain types of melanoma and lung cancer.

Before starting treatment, your doctor will test your cancer to confirm that it has a BRAF V600E or V600K mutation. This helps make sure that Mektovi is right for you.

Dosage Form and Strengths of Mektovi

Mektovi comes as a tablet that contains 15 mg of binimetinib. The tablet is yellow and oval-shaped.

Each dose usually includes more than one tablet, depending on what your doctor prescribes.

Mektovi Administration

Mektovi should be taken the right way to help the medication work better and lower the chance of side effects.
Take Mektovi orally twice daily (every 12 hours), with or without food.
Always take Mektovi with encorafenib unless your doctor says otherwise.
Swallow the tablets whole with a glass of water.
If you miss a dose, take it as soon as you remember. But skip it if your next dose is less than 6 hours away.
Do not take an extra dose if you vomit. Just take your next scheduled dose.
If encorafenib is stopped, your doctor may also stop Mektovi.
Store the tablets at room temperature and keep them in their original container.

Storage Information

Store Mektovi tablets at room temperature. Keep the tablets in their original bottle with the lid tightly closed. Protect the medication from moisture and heat.

Do not store Mektovi in the bathroom or places with high humidity. Keep it out of reach of children.

Mektovi Side Effects

Some Mektovi side effects are mild and often happen, like feeling tired, upset stomach, or muscle pain. Other side effects can be more serious, such as problems with the heart, liver, eyes, or muscles.

It is important to watch for changes in your feelings and let your doctor know if anything seems wrong. Some side effects may need quick medical help.

Common Side Effects

Feeling tired
Nausea
Diarrhea
Vomiting
Stomach pain
Muscle or joint pain
Blurred vision or vision changes
Constipation
Rash
Cough
Shortness of breath

Severe Side Effects

Fast heartbeat, swelling in the legs, or feeling lightheaded
Chest pain or swelling in arms or legs from blood clots
Vision loss, seeing halos or colored dots
Trouble breathing or coughing
Yellow skin, dark urine, or loss of appetite from liver problems
Muscle weakness, pain, or dark red urine
Bleeding in the brain or stomach, shown by headaches, vomiting blood, or black stool

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