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What is Retevmo (selpercatinib)? – Buy Retevmo 80mg Capsules online UK

Retevmo (selpercatinib) is a prescription medication used to treat certain types of cancer caused by abnormal genes called RET (rearranged during transfection).

Retevmo is mainly used for the treatment of:

Non-small cell lung cancer (NSCLC): Used in adults with locally advanced or metastatic NSCLC with a RET gene fusion.

Medullary thyroid cancer (MTC): Used in adults and children aged 2 years or older with advanced MTC requiring systemic therapy.

Thyroid cancer: Used in adults and children aged 2 years or older with advanced or metastatic thyroid cancer with a RET gene fusion, especially if radioactive iodine treatment has been ineffective.

Other solid tumors with RET gene fusion: Used when cancer has spread or progressed after prior treatment, or if no other satisfactory treatment options are available.

Before starting Retevmo, your healthcare provider will perform tests to confirm whether this medication suits you.

Important: Retevmo is not recommended for children under 2 years old and should not be used during pregnancy or while breastfeeding.

How Does Retevmo Work? – Order Retevmo 80mg Capsules online pharmacy

Retevmo works by blocking the RET gene, which is involved in the growth and spread of certain cancers.

When the RET gene undergoes mutations or changes, it sends signals that cause cancer cells to grow and divide uncontrollably.

By targeting and inhibiting the RET gene, Retevmo helps prevent these harmful signals, slowing or stopping tumor growth in cancers such as lung, thyroid, and other solid tumors.

Dosage Information and Usage

Retevmo is available in different dosage forms, such as tablets and capsules taken orally.

The specific dosage and schedule for Retevmo depends on the patient’s age, weight, and the condition being treated.

Dosage Form and Strengths of Retevmo

Retevmo comes in different forms and strengths to fit your needs.

Here are the available forms and strengths:

Capsules:

40 mg
80 mg

Tablets:

40 mg
80 mg
120 mg
160 mg

These dosage forms are designed for easy oral administration. Swallow Retevmo tablets or capsules whole without crushing or chewing them.

How to Use Retevmo? – Buy Retevmo 80mg Capsules no prescription

When using Retevmo, take it exactly as your doctor has prescribed.

Here are some important instructions on how to take Retevmo:

You can take Retevmo with or without food, but if you are taking a proton pump inhibitor (PPI), you should take it with food.

Do not crush or chew Retevmo tablets or capsules. Discuss other options with your doctor if you cannot swallow the capsules.

If you miss a dose, skip it if it is less than 6 hours until your next dose. If it is more than 6 hours, take the missed dose immediately. Never take an extra dose if you vomit after taking Retevmo. Just continue with your next scheduled dose.

If you experience side effects, your healthcare provider may adjust your dosage or temporarily stop the medication. It is important not to change your dosage without their guidance.

Retevmo Side Effects

While effective, Retevmo may cause a range of side effects. These can include common side effects like fatigue, diarrhea, and elevated liver enzymes, as well as more severe ones, such as heart problems, lung issues, and liver damage.

Common Side Effects

Swelling in the arms, legs, hands, and feet (edema)

Diarrhea
Tiredness (fatigue)
Dry mouth
Stomach-area (abdominal) pain
Constipation
Rash
Nausea
Headache

Severe Side Effects

Liver problems:

Yellowing of skin or eyes
Dark “tea-colored” urine
Sleepiness
Nausea
Vomiting
Stomach pain

Lung issues:

Shortness of breath
Persistent cough
Fever (which can be life-threatening)

High blood pressure:

Increased blood pressure
Headaches
Dizziness
Chest pain
Shortness of breath

Heart rhythm changes (QT prolongation):

Fainting
Dizziness
Irregular heartbeats

Bleeding problems:

Vomiting blood
Coughing up blood
Unusual bruising
Nosebleeds
Tumor lysis syndrome (TLS):
Weakness
Swelling
Shortness of breath
Muscle cramps
Seizures
Wound healing problems: Difficulty healing wounds, particularly during surgery
Low thyroid hormone levels (hypothyroidism):
Weight gain
Cold sensitivity
Extreme tiredness

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